Research Interests:
The study of structure property quantitative relationships in chemistry and
biology by means of correlation analysis. Applications of this work include chemical
reaction mechanisms, the estimation of chemical and physical properties and chemical
reactivities of chemical compounds, the design of bioactive molecules including
medicinal drugs and pesticides, and the prediction of environmental toxicities and other
properties.
summary of papers presented and published
M. CHARTON
Publications
(published or in press)
Chapters in
contributed volumes
22
Papers
Journals
92
Symposium volumes
14
Total
128
Preliminary publications
8
Miscellaneous publications
6
Total publications
142
Papers presented (appeared
in meeting abstracts, not yet
[ublished in full)
86
Overall total
227
PUBLICATIONS LIST - MARVIN CHARTON
PUBLISHED OR IN PRESS
1. Application of the Hammett Equation to Non-Aromatic Unsaturated Systems. I.
Trans-3-Substituted Acrylic Acids. M. Charton and M. Meislich, J. Am Chem. Soc., 80,
5940-5943 (1958).
2. Application of the Hammett Equation to the Ortho Substituted Benzene Reaction Series.
M. Charton, Can. J. Chem., 38, 2493-2499 (1960).
3. Application of the Hammett Equation to Acetylenic Systems. M. Charton, J. Org. Chem.,
26, 735-738 (1961).
4. Estimation of Hammett Substituent Constants. M. Charton, J. Org. Chem., 28,
3121-3124 (1963).
5. Application of the Hammett Equation to Cyclopropanes. M. Charton, J. Chem. Soc.,
1205-1212 (1964).
6. Electrical Effects of Ortho Substituents in Pyridines and Quinolines. M. Charton, J. Am.
Chem. Soc., 86, 2033- 2037 (1964).
7. Definition of Inductive Substituent Constants. M. Charton, J. Org. Chem., 29, 1222-1227
(1964).
8. Nature of Price-Alfrey q and Epsilon Parameters. M. Charton and A.J. Capato, J.
Polymer Sci., A2, 1321-1330 (1964).
9. Site of Basicity in Cinnoline, M. Charton, J. Chem. Soc., 5884-5885 (1964).
10. Application of the Hammett Equation to Non-Aromatic Unsaturated Systems. III. Dipole
Moments of Trans-Vinylene and Vinylidene Sets. M. Charton, J. Org. Chem., 30, 552-557
(1965).
11. Application of the Hammett Equation to Non-Aromatic Unsaturated Systems. IV.
Vinylidene and Heterovinylidene Sets. M. Charton, J. Org. Chem., 30, 557-560 (1965).
12. Application of the Hammett Equation to Non-Aromatic Unsaturated Systems. V.
Cis-Vinylene Sets; Composition of Electrical Effects. M. Charton, J. Org. Chem., 30,
974-977 (1965).
13. Application of the Hammett Equation to Amidines. M. Charton, J. Org. Chem., 30,
969-973 (1965).
14. Application of the Hammett Equation to Polycyclic Aromatic Sets. I. Quinolines and
Isoquinolines. M. Charton, J. Org. Chem., 30, 3341-3345 (1965).
15. Electrical Effect of Ortho Substituents in Imidizoles and Benzimidazoles. M. Charton,
J. Org. Chem., 30, 3346- 3350 (1965).
16. Application of the Hammett Equation to Substituent Effects on ã Donors in
Charge-Transfer Complex Formation. I. Singly Substituted Donors. M. Charton, J. Org.
Chem., 31, 2991-2996 (1966).
17. Application of the Hammett Equation to Substituent Effects on ã Donors in
Charge-Transfer Complex Formation. II. Multiply Substituted Donors. M. Charton, J. Org.
Chem., 31, 2996-3000 (1966).
18. Application of the Hammett Equation to Non-Aromatic Unsaturated Systems. VI. The
Diels-Alder Reaction. M. Charton, J. Org. Chem., 31, 3745-3751 (1966).
19. Substituent Effects in 1,10-Phenanthrolines. I. Equilibria. M. Charton, J. Org. Chem.,
31, 3739-3745 (1966).
20. The Calculation of Go for Axial-Equatorial Equilibria in Mono-Substituted
Cyclohexanes. M. Charton and B. I. Charton, J. Chem. Soc., B, 45-45 (1967).
21. The Variation of the Ortho Electrical Effect with Solvent. M. Charton and B.I. Charton,
J. Org. Chem., 33, 3872-3878 (1968).
22. A Linear Free Energy Relationship for Acceptor Strength in Charge-Transfer Complex
Formation. I. Substituted Benzene Donors. M. Charton, J. Org. Chem., 33, 3878-3882
(1968).
23. The Nature of the Ortho Effect. I. Electrophilic Aromatic Substitution. M. Charton, J.
Org. Chem., 34, 278- 285 (1969).
24. The Nature of the Ortho Effect. II. Composition of the Taft Es Parameters. M. Charton,
J. Am. Chem. Soc., 91, 615-618 (1969).
25. The Nature of the Ortho Effect. III. Acid Hydrolysis of Ortho Substituted Benzoates;
Esterification of Ortho Substituted Benzoic Acids. M. Charton, J. Am. Chem. Soc., 91,
619-623 (1969).
26. The Nature of the Ortho Effect. IV. Alkaline Hydrolysis of Ortho Substituted Benzoates.
M. Charton, J. Am. Chem. Soc., 91, 624-628 (1969).
27. Application of the Hammett Equation to Non-Aromatic Unsaturated Systems. VII.
Heterovinylene Sets. M. Charton and B.I. Charton, J. Org. Chem., 34, 1871-1876 (1969).
28. Substituent Effects at Elements Other than Carbon. I. Phosphorus Acids. M. Charton,
J. Org. Chem., 34, 1877-1881 1969).
29. Substituent Effects at Elements other than Carbon. II. Ionization Potentials. M. Charton
and B.I. Charton, J. Org. Chem., 34, 1882-1885 (1969).
30. The Nature of the Ortho Effect. V. Ortho Substituent Constants. M. Charton, J. Am.
Chem. Soc., 91, 6649-6654 (1969).
31. Annular Tautomerism in Nitrogen Heterocycles. I. Tetrazoles. M. Charton, J. Chem.
Soc., B, 1240-1244 (1969).
32. [C]* Olefinic Properties of Cyclopropanes. M. Charton, "Chemistry of the Alkenes", Vol.
2, J. Zabicky, (Ed.), John Wiley, New York, 1970, pp. 511-610.
33. Application of the Hammett Equation to Non-Aromatic Unsaturated Systems. VIII.
Ionization Potentials. M. Charton, Can. J. Chem., 48, 1748-1753 (1970).
34. The Nature of the Ortho Effect. VI. Polarographic Half-Wave Potentials. M. Charton
and B.I. Charton, J. Org. Chem., 36, 260-265 (1971).
35. The Nature of the Ortho Effect. VII. NMR Spectra. M. Charton, J. Org. Chem., 36,
2266-272 (1971).
36. The Nature of the Ortho Effect. VIII. Composition of the Ortho Effect as a Function of
Sidechain Structure. M. Charton, J. Org. Chem., 36, 882-887 (1971).
37. [C] The Quantitative Treatment of the Ortho Effect. M. Charton, Prog. Phys. Org.
Chem., 8, 235-317 (1971).
38. Application of the Hammett Equation to Non-Aromatic Unsaturated Systems. XII.
Physical Properties and Reactivity of the Ethynyl Proton. M. Charton, J. Org. Chem., 37,
3684-3687 (1972).
39. [C] Substituent Effects in Non-Aromatic Unsaturated Systems. M. Charton, Prog. Phys.
Org. Chem., 10, 81-204 (1973).
40. Application of the Hammett Equation to Non-Aromatic Unsaturated Systems. IX.
Electrophilic Addition to Olefins; X. Nucleophilic Addition to Olefins. M. Charton and B.I.
Charton, J. Org. Chem., 38, 1631-1636 (1973).
41. An Introduction to Linear Free Energy Relationships. I. An Entry. M. Charton, Chem
Tech, 502-511 (1974).
42. Calculation of Resonance Effect Reaction Parameters. I. Arylene, Vinylene and
Ethynylene Skeletal Groups. M. Charton, J. Org. Chem., 39, 2797-2799 (1974).
43. An Introduction to Linear Free Energy Relationships. II. Proximity Effects. M. Charton,
Chem Tech, 245-255 (1975).
44. Steric Effects. I. Esterification and Acid Catalyzed Hydrolysis of Esters. M. Charton,
J. Am. Chem. Soc., 97, 1552-1556 (1975).
45. The Nature of the Ortho Effect. XI. Reaction Rates of Carboxylic Acids with
Diphenyldiazomethane. M. Charton, J. Org. Chem., 40, 407-411 (1975).
46. Steric Effects. II. Base Catalyzed Ester Hydrolysis. M. Charton, J. Am. Chem. Soc., 97,
3691-3693 (1975).
47. Steric Effects. III. Bimolecular Nucleophilic Substitution. M. Charton, J. Am. Chem.
Soc., 97, 3694-3697 (1975).
48. Steric Effects. IV. E1 and E2 Eliminations. M. Charton, J. Am. Chem. Soc., 97,
6159-6161 (1975).
49. Steric Effects. V. Barriers to Internal Rotation. M. Charton and B.I. Charton, J. Am.
Chem. Soc., 97, 6472-6473 (1975).
50. Steric Effects. VI. Hydrolysis of Amides and Related Compounds. M. Charton, J. Org.
Chem., 41, 2906-2910 (1976).
51. Steric Effects. VII. Additional Upsilon Constants. M. Charton, J. Org. Chem., 41,
2217-2220 (1976).
52. Application of the Hammett Equation to Cyclophosphazenes. M. Charton and B.I.
Charton, Phosphorus and Sulfur, 3, 367-373 (1977).
53. Steric Effects. VIII. Racemization of Chiral Biphenyls. M. Charton, J. Org. Chem., 42,
2528-2529 (1977).
54. Steric Effects. IX. Substituents at Oxygen: Carbonyl Compounds. M. Charton, J. Org.
Chem., 42 3531-3535 (1977).
55. Steric Effects. X. Substituents at Nitrogen: Carbonyl Compounds. M. Charton, J. Org.
Chem., 42, 3535- 3538 (1977).
56. The Nature of the Electrical Effect of Alkyl Groups. I. The Validity of the Sigma*
Constants. M. Charton, J. Am. Chem. Soc., 99, 5687-5688 (1977).
57. [C]* The Predication of Chemical Lability Through Substituent Effects. M. Charton in
Design of Biopharmaceutical Properties Through Prodrugs and Analogs, E.B. Roche (Ed.),
American Pharmaceutical Society, Washington, D.C., 1977, pp. 228-280.
58. Steric Effects. XI. Substituents at Sulfur. M. Charton and B.I. Charton, J. Org. Chem.,
43, 1161-1165 (1978).
59. Steric Effects. XII. Substituents at Phosphorus. M. Charton and B.I. Charton, J. Org.
Chem., 43, 2383-2386 (1978).
60. Steric Effects. XIII. The Composition of the Steric Parameter as a Function of Alkyl
Branching. M. Charton, J. Org. Chem., 43, 3995-4001 (1978).
61. [C]* The Application of Linear Free Energy Relationships to Polycyclic Arenes and to
Heterocyclic Compounds. M. Charton in Correlation Analysis in Chemistry: Recent
Advances. N.B. Chapman and J. Shorter (Eds.), Plenum, New York, 1978, pp. 175-268.
62. The Nature of the Electrical Effect of Alkyl Groups. II. The Significance of the Taft
Sigma* Values for Alkyl Groups. M. Charton, J. Org. Chem., 44, 903-906 (1979).
63. Substituent Effects on Pyridine Nitrogen Reactivity. M. Charton, J. Org. Chem., 44,
2097-2099 (1979).
64. Significance of `Volume' and `Bulk' Parameters in Quantitative Structure - Activity
Relationships. M. Charton and B.I. Charton, J. Org. Chem., 44, 2284-2288 (1979).
65. The Dependence of Bond Angles Upon the Steric Effect. I. The X - M - X Bond Angles.
M. Charton, J. Am. Chem. Soc., 101, 7356-7361 (1979).
66. [S]* The Correlation of Biological Activities for Alkyl Substituted Systems. M. Charton
in "Proceedings of the Third Congress of the Hungarian Pharmacological Society, Budapest,
1979, Akademiaj Kiado, Budapest, 1980, pp. 211-220.
67. [C] Electrical Effect Substituent Constants for Correlation Analysis. M. Charton, Prog.
Phys. Org. Chem., 13, 119-251 (1981).
68. The Separation of Polar and Steric Effects. XIV. Kinetics of the Reactions of Benzoic
Acid and of Ortho Substituted Benzoic Acids with Diphenyldiazomethane in Various
Alcohols. M.H. Aslam, A.G. Burden, N.B. Chapman, J. Shorter and M. Charton, J. Chem.
Soc. Perkin Trans. II., 500-508 (1981).
69. The Separation of Polar and Steric Effects. XV. Kinetics of the Reactions of Benzoic
Acids and of Ortho Substituted Benzoic Acids with Diazodiphenylmethane in Various Aprotic
Solvents. M.H. Aslam, N.B. Chapman, J. Shorter and M. Charton, J. Chem. Soc. Perkin
Trans. II, 720-724 (1981).
70. Protein Folding and the Genetic Code: An Alternative Quantitative Model. M. Charton,
J. Theoret. Biol., 91, 115-123 (1981).
71. The Kinetics of the Reactions of Diazodiphenylmethane With 2,3-, 2,5-, and
2,6-Disubstituted Benzoic Acids and the Corresponding Monosubstituted Acids in Various
Alcohols and Aprotic Solvents. The Cumulative Effect of Substituents and the Solvent
Dependence of the Hammett Reaction Constants. M.H. Aslam, N.B. Chapman, M. Charton
and J. Shorter, J. Chem. Research, (S) 188 (1981); (M) 2301-2326 (1981).
72. Hyperconjugation as a Parameter in Correlation Analysis. M. Charton and B.I. Charton,
J. Org. Chem., 47, 8-13 (1982).
73. The Structural Dependence of Amino Acid Hydrophobicity Parameters. M. Charton and
B.I. Charton, J. Theoret. Biol., 99, 629-644 (1982).
74. Steric Effects on the Formation of Alkyl Radicals and Alkyl Carbenium Ions. M. Charton,
J. Chem. Soc. Perkins Trans. II, 97-104 (1983).
75. The Quantitative Description of Steric and Electrical Effects of Planar ã-Bonded Groups.
I. The Variation of Dihedral Angle with Size of an Adjacent Group. M. Charton, J. Org.
Chem., 48, 1011-1015 (1983).
76. The Quantitative Description of Steric and Electrical Effects of Planar ã-Bonded Groups.
II. Planar ã-Bonded Substitutents Ortho to a Non-Planar Active Site. M. Charton, J. Org.
Chem., 48, 1016-1021 (1983).
77. The Dependence of the Chou-Fasman Parameters on Amino Acid Sidechain Structure.
M. Charton and B.I. Charton, J. Theoret. Biol., 102, 121-134 (1983).
78. [C]* Directing and Activating Effects of Triply Bonded Groups. M. Charton in Chemistry
of the Functional Groups; Supplement C, S. Patai (Ed.), Wiley, New York, 1983, pp.
269-323.
79. [C] Introduction, M. Charton and I. Motoc, Topics in Current Chem., 114, 1-6 (1983).
80. [C] The Upsilon Parameter; Definition and Determination. M. Charton, Topics in Current
Chem., 114, 57-91 (1983).
81. [C] Volume and Bulk Parameters. M. Charton, Topics in Current Chem., 114, 107-118
(1983).
82. [S] The Estimation of Melting Points. M. Charton and B.I. Charton in QSAR in Design of
Bioactive Compounds, M. Kuchar (Ed.), J.R. Prous, Barcelona, 1985, pp. 25-40.
83. [S] The Dependence of Transport Parameters on Structure. Alkyl Group Variation. M.
Charton in QSAR in Design of Bioactive Compounds, M. Kuchar (Ed.), J.R. Prous, Barcelo-
na, 1985, pp. 41-51.
84. The Validity of the Revised F and R Electrical Effect Substituent Parameters. M.
Charton, J. Org. Chem., 49, 1997-2001 (1984).
85. [C]* Prodrug Lability Prediction Through the Use of Substituent Effects. M. Charton in
Drug and Enzyme Targeting., Vol. 112, Part A, Methods in Enzymology, K.J. Widder and R.
Green (Eds.), Academic Press, New York, 1985, pp. 323-340.
86. [S]* Bulk and Steric Parameters in Binding and Reactivity of Bioactive Compounds. M.
Charton in Rational Approaches to the Synthesis of Pesticides, P.S. Magee, J.J. Menn and
G.K. Koan (Eds.), American Chemical Society, Washington, D.C., 1984, pp. 247-278.
87. * Some Methods of Obtaining Quantitative Structure - Activity Relationships of
Quantitites of Environmental Interest. M. Charton, Environ. Health Perspect., 61, 229-238
(1985).
88. [S] QSAR for Peptide Bioactivity. M. Charton in Strategies in Drug Design, J.K. Seydel
(Ed.), Verlag Chemie, Weinheim, 1985, pp. 260-263.
89. [S] The Prediction of Chemical, Physical and Biological Properties of Haloaromatic
Compounds. M. Charton and B.I. Charton in Strategies in Drug Design, J.K. Seydel (Ed.),
Verlag Chemie, Weinheim, 1985, pp. 398-402.
90. [C]* Substituent Effects in Carbocations Substituted at Cationic Carbon. M. Charton in
Molecular Structures and Energetics 4, A. Greenberg and J.F. Liebman (Eds.), VCH
Publishers, Weinheim, 1987, pp. 261-317.
91. [S]* Environmental Properties of Phenols. M. Charton and B.I. Charton in "QSAR in
Toxicology and Chemistry," M. Tichy (Ed.), Prague, Elsevier, Amsterdam, 1985, pp. 53-63.
92. The Composite Parameter Method: Application to Calculated Stabilization Energies of
Strained and Unstrained Molecules. M. Charton, A. Greenberg, and T. A. Stevenson, J. Org.
Chem. 50, 2643-2646 (1985).
93 . Linear Free Energy Relationships Among Substituted Phenol Condensation Products.
T.F. DeRosa, E.M. Pierce and M. Charton, Macromolecules 18, 2277-2280 (1985).
94. Correlations Using Glass Transition Temperatures for Well Ordered Substituted Phenol
Condensation Products. T.F. DeRosa, E.M. Pierce and M. Charton, Macromolecules 18,
2280-2281 (1985).
95. The Ortho Effect in Pyridines. I. Polarographic Reduction of
2-Substituted-3-nitropyridines. M. Charton, R. Gawinecki, D. Rasala, W. Kraus, P. Tomasik
and Z. Lenard, Chem. Scripta 25, 334-339 (1985).
96. The Ortho Effect in Pyridines. II. Polarographic Reduction of
4-Substituted-3-nitropyridines. M. Charton, R. Gawinecki, D. Rasala, W. Kraus and P.
Tomasik, Chem. Scripta 25, 340-344 (1985).
97. The Ortho Effect in Pyridines. V. An Intervention of the Intramolecular Hydrogen Bond.
M. Charton, R. Gawinecki, D. Rasawa, W. Kraus and P. Tomasik, Chem. Scripta 25, 350-
355 (1985).
98. The Quantitative Description of Side Chain Effects on Binding to Proteins. M. Charton,
Int. J. Peptide Protein Res., 28, 201-206 (1986).
99. * Organism Parameterization in QSAR. M. Charton, Acta Pharmaceut. Jugoslav. 36,
97-118 (1986).
100. [S]* A General Treatment of Electrical Effects; Applications to Quantum Chemically
Calculated Substitutent Effects. M. Charton, Stud. Org. Chem. (Amsterdam) 31, 537-544
(1987).
101. [S] QSAR for Peptide Bioactivity. Further Studies. M. Charton and B.I. Charton, QSAR
in Drug Design and Toxicology, D. Hadzi and B. Jerman-Blazic (Eds.), Elsevier, Amsterdam,
1987, pp. 285-290.
102. [S] QSAR for Enzymatic Reactions of Amino Acids and their Derivatives. M. Charton,
QSAR in Drug Design and Toxicology, D. Hadzi and B. Jerman-Blazic (Eds.), Elsevier,
Amsterdam, 1987, pp. 291-294.
103. [C]* A General Treatment of Electrical Effects. M. Charton, Prog. Phys. Org. Chem.,
16, 287-315 (1987).
104. Contributions of Steric, Electrical and Polarizability Effects in Enantioselective
Hydrolyses with Rhizopus nigricans: A Quantitative Analysis. M. Charton and H. Ziffer, J.
Org. Chem. 52, 2400-2403 (1987).
105. Correlation Between the Glass Transition Temperatures of Polymer Mixtures and
Intermolecular Force Parameters. T.K. Kwei, E.M. Pearce, J.R. Pennacchia and M. Charton,
Macromolecules 20, 1174-1176 (1987).
106. The Quantitative Description of Small Molecule Binding to Abiotic Polymers. M.
Charton, J. Polymer Sci. A. 26, 1265-1275 (1988).
107. Structural Effects on Radical Reactions. 1. Homolytic Aromatic Substitution. M.
Charton and B.I. Charton, Bull. Soc. Chim. Fr. 199-210 (1988).
108. An Analysis of Complex Alkyl Substituent Effects in the Water-Catalyzed Hydrolyses
of 1-Acyl-1,2,4-triazoles. H.J. Mooij, J.B.F.N. Engberts and M. Charton, Rec. Trav. Chim.
Pays-Bas 107, 185-189 (1988).
109. [C]* Directing and Activating Effects of Doubly Bonded Groups. M. Charton in The
Chemistry of the Functional Groups. Supplement A, The Chemistry of Double Bonded
Functional Groups., Vol. 2, Part 1, S. Patal and Z. Rappaport (Eds.), Wiley, New York, 1989,
pp. 239-298.
110. Amino Acid Side Chain Parameters for Correlation Studies in Biology and
Pharmacology. J.-L. Fauchere, M. Charton, L.B. Kier, V. Pliska and A. Verloop, Int. J.
Protein Peptide Res. 32, 269-278(1988).
111. [S]* The Nature of Transport Parameters. M. Charton in Trends in Medicinal Chemistry
'88, H. van der Goot, G. Domany, L. Pallos and H. Timmerman (Eds.), Elsevier, Amsterdam,
1989, pp. 89-108.
112. [S]* The Quantification of Peptide Bioactivities. Peptide Antibiotics. M. Charton in
QSAR Quantitative Structure Activity Relationships in Drug Design, J.-L. Fauchere (Ed.),
Allen R. Liss, New York, 1989, pp. 307-312.
113. [C] The Quantitative Description of Properties and Bioactivities of Amino Acids,
Peptides and Proteins. M. Charton, Prog. Phys. Org. Chem. 18, 163-284 (1990).
114. [C]* Directing and Activating Effects of Chalcogen Substituents. M. Charton in The
Chemistry of Sulfenic Acids, Esters and Derivatives, S. Patai, ed., Wiley, New York, 1990,
pp.657-700.
115. The Quantification of Protein Bioactivity. Phage T4 Lysozymes Substituted at Residue
86. M. Charton, Coll. Czech. Chem. Commun. 55, 273-281 (1990).
116. Antagonists as "Affinity Probes" for Peptide Hormone Receptors: QSAR Studies on
Oxytocin Receptor in the Rat Myometrium. V. Pliska and M. Charton, J. Receptor Res. 11,
59-78 (1991).
117. [C]* The Quantitative Description of Steric Effects. M. Charton, Stud. Org. Chem., 42,
629-687 (1992).
118. * The Quantitative Description of the Variation of Protein Properties and Bioactivities
with Side Chain Structure. M. Charton, J. Chim. Phys. 89, 1689-1701 (1992).
119. Peptide Renin Inhibitor QSAR. M. Charton, QSAR in Design of Bioactive Compounds.
2, J. Prous, Barcelona, 1992, pp. 329-346.
120. [C]* Substituent Effects of Arsenic, Antimony and Bismuth Groups. M. Charton in The
Chemistry of Arsenic, Antimony and Bismuth, S. Patai, ed., Wiley, New York, 1994, p. 367-
439.
121. The Quantitative Description of Structural Effects on Melting Points of Substituted
Alkanes. M. Charton and B. I. Charton, J. Phys. Org. Chem. 7, 196-206 (1994).
122. [C]* Substituent Effects of Germanium, Tin, and Lead Groups. M. Charton in The
Chemistry of Organic Germanium, Tin and Lead Compounds, S. Patai, Ed., Wiley,
Chichester, 1995, p. 603-664.
123. [S]* Transport Parameter Dependence on Intermolecular Forces. M. Charton, Classical
and 3-D QSAR in Agrochemistry and Toxicology, C. Hansch and T. Fujita, Eds., American
Chemical Society, Washington, D. C., 1995, p. 75-95.
124. [C] The Estimation of Electrical Effect Substituent Constants for Correlation Analysis.
M. Charton, Advances in Quantitative Structure Property Relationships 1, 171-219 (1996).
125. [C]* The Application of the Intermolecular Force Equation to Bioactivity. Peptide and
Protein QSAR. in Lipophilicity in Drug Action and Toxicity, V. Pliska, B. Testa and J. van der
Waterbeemd, Eds., VCH Weinheim, 1996, p. 387-400
126. Substituent Effects on an Inverse Electron Demand Hetero Diels - Alder Reaction in
Aqueous Solution and Organic Solvents: Cycloaddition of Substituted Styrenes to Di(2-
pyridyl) - 1,2,4,5 - tetrazine. J. W. Wijnen, S. Zavarise, J. B. F. N. Engberts, and M. Charton,
J. Org. Chem. 61, 2001-2005 (1996).
127. Synthesis and Characterization of Substituted Benzoylhydrazones of Naloxone. G. R.
Ciszewska, J. A. Ginos, M. Charton, K. M. Standifer, A. I. Brooks, G. P. Brown, J. P. Ryan-
Moro, I. Berzetei-Gurske, L. Toll, and G. W. Pasternak, Synapse 24, 193-201(1996).
128. Structural Effects on Dienes and Polyenes. M. Charton in The Chemistry of Dienes and
Polyenes, Z. Rappoport, Ed., Wiley, Chichester, 1997. in press.
[C] indicates a chapter in a contributed volume.
[S] indicates a symposium volume.
* indicates an invited publication.
PRELIMINARY PUBLICATIONS
1. Substituent Effects in Carbocations Substituted at a Charged Carbon Atom. M. Charton
and B.I. Charton, Bull. Soc. Chim. Belg., 91, 373 (1982).
2. Substituent Effects in Carbanions Substituted at a Charged Carbon Atom. M. Charton,
Bull Soc. Chim. Belg., 91, 374 (1982).
3. Steric Effects on Alkyl Bioactivity. The Expanded Bioactivity Branching Equation. M.
Charton in Quantitative Approaches to Drug Design, J. Dearden (Ed.), Elsevier,
Amsterdam, 1983, pp. 67-68.
4. The Organism as a Variable in QSAR. M. Charton in Quantitative Approaches to Drug
Design, J. Dearden (Ed.), Elsevier, Amsterdam, 1983, pp. 69-70.
5. Amino Acid Properties and Bioactivities as a Function of Side Chain Structures. M.
Charton and B.I. Charton in Quantitative Approaches to Drug Design, J. Dearden (Ed.),
Elsevier, Amsterdam, 1983, pp. 260-261.
6. Quantification of Binding to Heme Proteins. M. Charton, Proc. VIIIth Intl. Symp. Med.
Chem., Uppsala, 1984, pp.289-290.
7. * QSAR for Toxicities of Carbonyl Compounds. M. Charton, Preprint Extended Abstracts
Div. Env. Chem. A.C.S., 28, No. 1, 1987.
8. Quantitative Structure-Activity Relationships (QSAR) of Neurohypophyseal Hormone
Analogs acting as Oxytocin Inhibitors on Uterus in Vitro. V. Pliska and M. Charton, Peptides -
Chemistry, Structure and Biology. Proc. 11th Am. Peptide Symposium, J. E. Rivier and G.
R. Marshall, Eds., Escom Science Publishers, Leiden, 1990, pp. 290-292.
MISCELLANEOUS PUBLICATIONS
1. Book Review: Advances in Linear Free Energy Relationships, N.B. Chapman and J.
Shorter (Eds.), M. Charton, Chem. Tech. (1972).
2. X-T Parameters. M. Charton in Summary Report of the Workshop on Structure Activity
Concepts in Environmental Science, NTIS PB85-137339, Springfield, VA pp. 96-99.
3. Recommendations for Reporting the Results of Correlation Analysis in Chemistry
Using Regression Analysis. M. Charton, S. Clementi, S. Ehrenson, O. Exner, J. Shorter
and S. Wold, Quan. Struct.-Act. Relat. 4, 29 (1985).
4. Book Review: Correlation Analysis of Chemical Data by O. Exner, (Ed. by J. Shorter),
M. Charton, J. Am. Chem. Soc. 111, 5507 (1989).
5. The Quantitative Description of Steric Effects: A Brief Review. Kemiai Kozlemenyek
73, 13-27 (1991).
6. Book review: EXPLORING QSAR. Fundamentals and applications in chemistry and
biology. By Corwin Hansch and Albert Leo; EXPLORING QSAR. Hydrophobic, electrical
and steric constants. By Corwin Hansch, Albert Leo, and David Hoekman. Chem.
Intelligencer, in press.
PAPERS PRESENTED
(Appeared in meeting abstracts, not yet published in full)
1. Applications of the Hammett Equation to Non-Aromatic Unsaturated Systems. II.
Quinone Oxidation-Reduction Potentials. M. Charton, Abstr. 132nd Mtg. Am. Chem. Soc.,
1957, p. 73-P.
2. Calculation of Hammett Reaction Parameters. I. Ionization of Carboxylic Acids. M.
Charton, Abstr. 137th Mtg. Am. Chem. Soc., 1960, p. 92-O.
3. Calculation of Hammett Reaction Parameters. II. Saponification of Esters. M. Charton,
Abstr. 140th Mtg. Am. Chem. Soc., 1961, p. 57-T.
4. The Variation of the Hammett Reaction Parameters with Constant Substituents. M.
Charton, Abstr. 145th Mtg. Am. Chem. Soc., 1963, p. 63-T.
5. Calculation of åI Constants. M. Charton, Abstr. 148th Mtg. Am. Chem. Soc., 1964, p.
56-V.
6. A Linear Free Energy Relationship for Solvent Effects on Charge Transfer Equilibria.
M. Charton, Abstr. 152nd Mtg. Am. Chem. Soc., 1966, p. 195-V.
7. Annular Tautomerism in Nitrogen Heterocycles. III. Cinnolinium Ions. Abstr. 1st Intl.
Cong. Heterocyclic Chem., 1967, No. 77.
8. Annular Tautomerism in Nitrogen Heterocycles. II. Pyrazinium and Pyridazinium Ions.
M. Charton, Abstr. 154th Mtg. Am. Chem. Soc., 1967, p. 137-S.
9. A Linear Free Energy Relationship for Charge Transfer Acceptor Strength. II.
Polycyclic Arene Donors. M. Charton, Abstr. 154th Mtg. Am. Chem. Soc., 1967, p. 130-V.
10. The Ortho Electrical Effect in Infrared Spectra. M. Charton and B. I. Charton, Abstr.
3rd M. A. R. M. Am. Chem. Soc., 1968, p. 89.
11. The Polar Effect in Conformational Equilibria. II. M. Charton and B. I. Charton, Abstr.
3rd M. A. R. M. Am. Chem. Soc., 1968, p. 89.
12. Substituent Effects in 1,10- Phenanthrolines. II. M. Charton and B. I. Charton, Abstr.
155th Mtg. Am. Chem. Soc., 1968, p. 17-M.
13. A Linear Enthalpy Relationship for the Estimation of Ionization Potentials. M. Charton,
Abstr. 155th Mtg. Am. Chem. Soc., 1968, p. 112-S.
14. Substituent Effects Upon Dipole Moments of Substituted Arenes. M. Charton, Abstr.
156th Mtg. Am. Chem. Soc., 1968, p. 78-P.
15. Correlation of Dipole Moments for meta and para Disubstituted Benzenes with the
Extended Hammett Equation. M. Charton, Abstr. 157th Mtg. Am. Chem. Soc., 1969, p.
17-P.
16. Substituent Effects at Elements other than Carbon. III. Physical Properties of
Phosphorus Compounds. S. Finger and M. Charton, Abstr. 5th M. A. R. M. Am. Chem.
Soc., 1970, p.
17. Nature of the Ortho Effect. X. Infrared Spectra; OH, NH2, CH, CN, and SO2
Absorptions. M. Charton, Abstr. 160th Mtg. Am. Chem. Soc., 1970, p. 182-P.
18. A Reexamination of the Edwards Equation. M. Charton, Abstr. Metrochem 71 Mtg.
Am. Chem. Soc., 1971, p. 16.
19. Application of the Hammett Equation to Dipole Moments of the Group IV Elements. M.
Charton and B. I. Charton, Abstr. Metrochem 71 Mtg. Am. Chem. Soc., 1971, p. 16.
20. Application of the Hammett Equation to Non-Aromatic Unsaturated Systems. XI. NMR
Proton Chemical Shifts. M. Charton, Abstr. 162nd Mtg. Am. Chem. Soc., 1917, p. 140-P.
21. Steric Effects. XV. Addition of Nucleophiles to Aldehydes and Ketones. M. Charton,
Abstr. 3rd I. U. P. A. C. Conf. Phys. Org. Chem., Montpellier, 1976, p. 16-17.
22. Steric Effects in Reactions of Silanes. M. Charton and B. I. Charton, Abstr. 5th Intl.
Symp. Organosilicon Chem., Karlsruhe, 1978, p. 190.
23. Proximity Effects in Orthocarboranes. M. Charton and B. I. Charton, Abstr. 2nd Intl.
Symp. Inorg. Ring Systems, Gottingen, 1978, Wed B 11.25H.
24. The Nature of the Electrical Effect in "Non-Classical" Carbonium Ions. M. Charton
and B. I. Charton, Abstr. 4th I. U. P. A. C. Conf. Phys. Org. Chem., York, 1978, p. O26.
25. Substituent Effects in Substituted Ferrocenes. I. Transmission through the Ferrocene
Skeletal Group. M. Charton and B. I. Charton, Abstr. 1st Eur. Symp. Org. Chem., 1979, p.
38.
26. The Application of Correlation Analysis to Ionization Potentials. M. Charton and B. I.
Charton, Abstr. 1st Euchem Conf. Correlation Anal. Org. Chem., Assisi, 1979, p. O-1.
28. Steric Effects XVI. The Extended Branching Equation. M. Charton, Abstr. 1st Euchem
Conf. Correlation Anal. Org. Chem., Assisi, 1979, p. P3.
29. The Utility of å* Constants as a Substituent Parameter in Correlation Analysis. M.
Charton, Abstr. 1st Euchem Conf. Correlation Anal. Org. Chem., Assisi, 1979, p. P4.
30. Nature of the Electrical Effects of Alkyl Groups. 3. Electrical Effects of Alkyl Groups in
the Gas Phase. M. Charton, Abstr. 1st Euchem Conf. Correlation Anal. Org. Chem.,
Assisi, 1979, p. P21.
31. The Nature of the NMR Q Parameter. M. Charton and B. I. Charton, Abstr. 2nd Chem.
Congr. North Am. Continent, 1980, p. Phys 243.
32. Ionization Potentials of Heterovinylene and Heteroethynylene Compounds. M.
Charton, Abstr. 2nd Chem. Congr. North Am. Continent, 1980, p. Phys 244.
34. Electrical and Steric Effects of Substituents Bonded to Phosphorus. Tricoordinate
Phosphorus. M. Charton, E. Gearon, and B. I. Charton, Abstr. Intl. Conf. Phosphorus
Chem., Durham, N. C., 1981, p.
35. Extensions of the Alkyl Bioactivity Branching Equation. M. Charton, Abstr. 2nd
Noordwijkerhout IUPAC-IUPHARM Symp., Strategy in Drug Design, 1981, p. 79.
36. An Overview of the Two Parameter Approach to the Quantitative Description of
Electrical Effects. M. Charton, Abstr. 2nd Euchem Conf. Correlation Anal. Org. Chem.,
Hull, 1982, p. P/28.
37. The Quantitative Description of Steric and Electrical Effects of Planar ã Bonded
Groups with Particular Reference to the Ortho Effect. M. H. Aslam, A. G. Burden, N. B.
Chapman, J. Chorter, and M. Charton, Abstr. 2nd Euchem Conf. Correlation Anal. Org.
Chem., Hull, 1982, p. P/3.
38. The Dependence of Alkyl Steric Parameters on Branching; A Further Study. M.
Charton, Abstr. 2nd Euchem Conf. Correlation Anal. Org. Chem., Hull, 1982, p. P/28.
39. Quantitative Structure-Activity Relationships for Environmental Toxicity: Applications
of the Bioactivity Branching Equation. M. Charton and B. I. Charton, Abstr. 3rd Ann. Mtg.
Soc. Env. Tox. Chem., 1982, p. 47.
40. Steric Effects in Electrophilic Aromatic Substitution: A Quantitative Treatment. M.
Charton, Abstr. 10th Mtg. React. Mech. Grp. Roy. Soc. Chem., Maynooth, 1983, p. 51.
41. Ionization Potentials of Substituted Ethylenes and Acetylenes. M. Charton, Abstr.
186th Mtg. Am. Chem. Soc., 1983, p. Phys. 90.
42. Dispersion Forces in Arene Charge Transfer Complex Formation. M. Charton, Abstr.
186th Mtg. Am. Chem. Soc., 1983, p. Phys. 91.
43. The Quantitative Description of Steric Effects on Charge Transfer Complex
Formation. M. Charton, Abstr. 186th Mtg. Am. Chem. Soc., 1983, p. Phys. 92.
44. The Dependence of the Zimm-Bragg Protein Conformational Parameters on Amino
Acid Side Chain Structure. M. Charton, Abstr. 18th M. A. R. M. Am. Chem. Soc., 1984, p.
39, No. 14.
45. The Relationship Between Electrical Effect Substituent Constants and
Electronegativity. M. Charton, Abstr. 18th M. A. R. M. Am. Chem. Soc., 1984, p. 109, No.
260.
46. The Estimation of Steric Parameters for Lone Pairs on Atoms of Second, Third, and
Fourth Period Elements. M. Charton, Abstr. 18th M. A. R. M. Am. Chem. Soc., 1984, p.
110, No. 261.
47. Dependence of Bond Angles Upon the Steric Effect. II. Tetrahedral SiZ3 and GeZ3
Groups. M. Charton, Abstr. 18th M. A. R. M. Am. Chem. Soc., 1984, p. 131, No. 326.
48. Interrelationships Among Measures of Atomic Size. M. Charton, Abstr. Intl. Symp.
Strain and Steric Effects in Org. Chem., Bangor, 1985, p. C27.
49. The Quantitative Description of Buttressing Effects. M. Charton and B. I. Charton,
Abstr. Intl. Symp. Strain and Steric Effects in Org. Chem., Bangor, 1985, p. B16.
50. Peptide Hydrophobicity as a Function of Side Chain Structure. M. Charton and B. I.
Charton, Abstr. 3rd Euchem Conf. Correlation Anal. Org. and Biol. Chem., Louvain la
Neuve, 1985, p. B16.
51. The Validation of the Omega Method. M. Charton, Abstr. 3rd Euchem Conf.
Correlation Anal. Org. and Biol. Chem., Louvain la Neuve, 1985, p. C15.
52. The Dependence of Protein Conformation on Amino Acid Side Chain Structure.
Further Studies. M. Charton and B. I. Charton, Abstr. 3rd Noordwijkerhout Symp., 1985,
p. 101.
53. Amino Acid Properties as a Function of Side Chain Structure. Further Studies. M.
Charton and B. I. Charton, Abstr. 3rd Noordwijkerhout Symp., 1985, p. 102.
55. The Transmission of Electrical Effects by sp3 Hybridized Carbon Atoms. M. Charton
and B. I. Charton, Abstr. 8th I. U. P. A. C. Conf. Phys. Org. Chem., Tokyo, 1986, p. 186.
56. The Application of the LDR Equation to Mechanistic Studies. M. Charton, Abstr.
Kyushu Symp. Phys. Org. Chem., Fukuoka, 1986, p. 132-
57. The Dependence of Protein Secondary Structure on the Nature of the Amino Acid
Side Chains. M. Charton, Abstr. 4th Mtg. on Stereochemistry, Liblice, 1987, p. 14a-14b.
59. Structural Effects on Radical Reactions. 2. Homolytic Substitution at sp3 Hybridized
Carbon. M. Charton and B. I. Charton, Abstr. 1st Eur. Symp. Org. Reactivity, Paris, 1987,
p. P34.
61. Structural Effects on Radical Reactivity. 3. Radical Substituent Effect Parameters. M.
Charton and B. I. Charton, Abstr. 9th I. U. P. A. C. Conf. Phys. Org. Chem., Regensberg,
1988, p. A33.
62. The Quantification of Structural Effects on Radical Reactivity. M. Charton and B. I.
Charton, Abstr. Conf. Trends in Phys. Org. Chem., Montegrotto 1988
63. The Quantification of Electrical Effects of Substituents Bonded to Elements other than
Carbon. M. Charton and B. I. Charton, Abstr. 2nd Eur. Symp. Org. Reactivity, Padova,
1989, p. 58.
64. Electrical Effects of Substituents Bonded to Elements other than Carbon. Ionization
Potentials. M. Charton and B. I. Charton, Abstr. 2nd Eur. Symp. Org. Reactivity, Padova,
1989, p. 127.
65. A Modified Yukawa-Tsuno Equation. M. Charton and B. I. Charton, Abstr. 10th Intl.
Conf. Phys. Org. Chem., Haifa, 1990, p. 24.
66. Conformational Equilibria in 1,2-Disubstituted Ethanes. M. Charton and B. I. Charton,
Abstr. 10th Intl. Conf. Phys. Org. Chem., Haifa, 1990, p. 145.
67. The Quantitative Description of Electrical Effects. M. Charton, Proc. Chemometrics II,
Brno, 1990, p. 20-22.
68. Temperature as a Parameter in Correlation Analysis. M. Charton and B. I. Charton,
Proc. Chemometrics II, Brno, 1990, p. 130.
69. The Quantitative Description of the Variation of Protein Properties and Bioactivities
with Side Chain Structure. M. Charton, Abstr. V-th Intl. Conf. Correlation Anal. Org.
Chem., Paris, 1991, p. L-10.
70. Hydrogen Bonding in Liquid Ammonia. M. Charton and B. I. Charton, Abstr. V-th Intl.
Conf. Correlation Anal. Org. Chem., Paris, 1991, p. A-16.
71. Buttressing Effects. 2. Benzoic Acid Ionization. M. Charton and B. I. Charton, Abstr.
3rd Eur. Symp. Org. Reactivity, G”teborg, 1991, p. 85.
72. Solvent Effects on the Ionization of Benzoic Acids. M. Charton and B. I. Charton,
Abstr. 3rd Eur. Symp. Org. Reactivity, G”teborg, 1991, p. 102.
73. Dependence of à-Helix Formation on Sidechain Structure. M. Charton and B. I.
Charton, Abstr. Fourth Chemical Congress of North America, New York, 1991, BIOL 37.
74. Dependence of Membrane Protein Prediction Scales on Sidechain Structure. M.
Charton and B. I. Charton, Abstr. Fourth Chemical Congress of North America, New York,
1991, BIOL 38.
75. Solvent Effects on Enzyme Reactivity. M. Charton and B. I. Charton, Abstr. Fourth
Chemical Congress of North America, New York, 1991, BIOT 247.
76. Solvent Effects on the Ionization of Benzoic Acids. 2. Binary mixtures of water and
organis solvents. M. Charton, Abstr. Fourth Kyushu International Symposium on Physical
Organic Chemistry, Fukuoka/Ube, 1991, p. 42-48.
77. The Nature of Radical Structural Effect Parameters. M. Charton, Abstr. 11th Intl. Conf.
Phys. Org. Chem., Ithaca, N. Y., 1992, p. 97.
78. Solvent Effects on Ortho Substituted Benzoic Acids. The Reaction with
Diazodiphenylmethane. M. Charton and J. Shorter, Abstr. 11th Intl. Conf. Phys. Org.
Chem., Ithaca, N. Y., 1992, p. 148.
79. Solvent Effects on the Acidity of Substituted Acetic Acids. M. Charton and B. I.
Charton, Abstr. 11th Intl. Conf. Phys. Org. Chem., Ithaca, N. Y., 1992, p. 149.
80. Quantitative Description of the Aqueous Acidity of Oxyacids. M. Charton, Abstr. 27th
M. A. R. M. Am. Chem. Soc., 1993, p. 85-86.
81. Estimation of Electrical Effect Substituent Constants. M. Charton, Abstr. 27th M. A. R.
M. Am. Chem. Soc., 1993, p. 128-129.
82. Estimation of Steric Effect Parameters: Further Advances. M. Charton and C.
Sirovich, Abstr. 27th M. A. R. M. Am. Chem. Soc., 1993, p. 129.
83. Melting Points of Substituted Ethenes, Benzenes, and Naphthalenes. M. Charton and
B. I. Charton, Abstr. 27th M. A. R. M. Am. Chem. Soc., 1993, p. 129-130.
84. Solvent Effects on the Ionization of Phenols. M. Charton and B. I. Charton, Abstr.
27th M. A. R. M. Am. Chem. Soc., 1993, p. 130.
85. The Mode of Transmission of Electrical Effects. M. Charton and B. I. Charton, Abstr.
Fourth Kyushu International Symposium on Physical Organic Chemistry, Fukuoka, 1993,
p. 42-44.
87. The Ortho Effect in Proton Transfer Reactions of Heteroarenes. M. Charton and P. J.
Taylor, Abstr. 12th Intl. Conf. Phys. Org. Chem., Padova, 1994, p. 183.
88. Substituent Constants for the Empirical Correlation of Electrical Effects. M. Charton
and B. I. Charton, Abstr. VI-th Intl. Conf. Correlation Anal. in Chem., Prague, 1994, p. O-
1.
89. Hydrogen Bonding Contribution to Lipophilicity Parameters. 1. Hydrogen Acceptor
Parameters. M. Charton and B. I. Charton, Abstr. Intl. Symp. Lipophilicity in Drug
Research and Toxicology., Lausanne, 1995, p. O-3.
90. The Mode of Transmission of Electrical effects. 2. Further (and hopefully final)
Results.M. Charton and B. I. Charton, Abstr. Sixth Kyushu International Symposium on
Physical Organic Chemistry, Fukuoka, 1995, p. 145-150.
91. The segmental model: A multiparametric description of steric effects. Abstr. 210th
Mtg. Am. Chem. Soc., 1995, p. COMP. .
95. Electrical effects and reaction mechanism: the LDR model. I. Substituent effects on
nonclassical carbenium ions. Abstr. VII-th Intl. Conf. Correlation Anal. in Chem.,
Fukuoka, 1996, p. 35